COVID-19感染对辅助生殖方法结果的影响
Niloofar Poursaadat1, Pershang Nazemi2, Saeideh Shams Zamenjani1
1Department of Infertility, Yas Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Journal of family & reproductive health
|July 16, 2024
概括
在接受生育治疗的妇女中,COVID-19感染显著降低了卵细胞产量和高质量的胚胎数量. 这影响了辅助生殖技术 (ART) 的成功率.
科学领域:
- 生殖医学 生殖医学
- 传染性疾病 传染性疾病
- 胚胎学 胚胎学
背景情况:
- 众所周知,COVID-19对卵细胞和胚胎有潜在的致病作用.
- 关于COVID-19对辅助生殖技术 (ART) 结果的具体影响的数据有限.
研究的目的:
- 调查COVID-19感染对ART方法结果的影响.
- 为了比较卵细胞产量和胚胎质量在妇女和没有COVID-19在卵细胞采集期间.
主要方法:
- 一项涉及190名不育妇女的病例控制研究,这些妇女在雅斯医院试管婴儿科接受了卵细胞采集.
- 病例组:女性在刺穿日检测出COVID-19阳性. 控制组:女性在刺穿日呈COVID-19阴性.
- 结果措施包括卵细胞检索数,胚胎数量和质量.
主要成果:
- 与对照组 (9.07) 相比,COVID-19阳性组 (6.68) 检索的卵细胞的平均数量显著低于对照组 (9.07).
- 在两组之间的胚胎平均数量中没有发现统计学上显著的差异.
- 在COVID-19阳性组中观察到更高的C级胚胎频率 (1.08对0.57),超过一半的这些病例中没有A级胚胎.
结论:
- 卵细胞检索当天的COVID-19感染与卵细胞数量减少有关.
- 接受ART的COVID-19阳性女性产生了更少的高质量胚胎,影响了生育治疗的成功.
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