在Toxocara Spp.之间的协会. 暴露和精神分裂症:一个病例对照研究
Keivan Sahebi1, Pouriya Akbari1, Fattaneh Mikaeili2
1Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Iranian journal of parasitology
|July 16, 2024
概括
这项研究发现,精神分裂症患者和健康人群之间的毒素感染率没有显著差异. 需要对更大,临床匹配样本进行进一步的研究,以澄清托克索卡拉暴露与精神分裂症之间的关联.
科学领域:
- 传染性疾病 传染性疾病
- 神经科学是一个神经科学.
- 流行病学 流行病学
背景情况:
- 毒病是一种动物性寄生虫感染.
- 由于自我护理障碍,精神分裂症患者的风险可能会增加.
- 在Toxocara spp.之间的关联. 暴露和精神分裂症需要调查.
研究的目的:
- 为了评估Toxcara spp.之间的关联. 暴露和精神分裂症.
- 为了比较精神分裂症患者与健康对照者的毒病的血清流行率.
主要方法:
- 一项涉及109名精神分裂症患者和104名健康对照者的病例控制研究.
- 血清样本通过ELISA对抗托克索卡拉IgG抗体进行了测试.
- 通过风险因素调查问卷收集的数据.
主要成果:
- 精神分裂症患者中毒素病的血清流行率为11.0%,对照组为9.6%.
- 群体之间血清流行率没有统计学上显著的差异 (OR=1.16,P=0.915).
- 在单变量分析中,与未洗过的产品消费和农村居住相关的较高血清阳性,但在多变量分析中不显著.
结论:
- 在精神分裂症患者和健康对照人群之间,毒素病血清发病率没有显著差异.
- 与先前研究的不一致性凸显了需要更大规模,临床匹配的研究.
- 需要进一步的研究,以了解托克索卡拉暴露与精神分裂症之间的复杂关系.
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