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作为强大的胆酶抑制剂的巴比酸盐-硫酸盐混合体:设计,合成和分子建模研究

Asmaa F Kassem1,2, Mohamed A Omar2, Ahmed Temirak2

  • 1Department of Chemistry, College of Science & Humanities in Al-Kharj, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.

Future medicinal chemistry
|July 16, 2024
PubMed
概括

新的巴比酸盐衍生物显示出对乙胆酶 (AChE) 和丁胆酶 (BChE) 的强烈抑制. 化合物3r是顶级的ACHE抑制剂,而3q导致BCHE抑制,没有观察到细胞毒性.

关键词:
这是阿尔茨海默氏症.抗氧化剂是一种抗氧化剂.巴比酸盐 - 硫酸盐是什么胆化酶是一种胆化酶.分子建模分子建模

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