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Updated: Jun 21, 2025

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing
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Published on: May 5, 2023

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重新设计的导向RNA使得DNA循环和接触能够调节大肠杆菌中的抑制.

Yunshi Yang1, Iris Rocamonde-Lago1, Boxuan Shen1,2

  • 1Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Stockholm 17177, Sweden.

Nucleic acids research
|July 16, 2024
PubMed
概括

研究人员开发了一种双导向RNA (dgRNA),它连接两个单导向RNA. 这项创新能够准遥远的DNA区域,提供了使用dCas9和RNA重塑染色体构造的最小系统.

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