患有牛皮的孕妇的药物使用模式:台湾的一项全国性研究
Chien-Hua Ou1,2, Li-Ting Kao1,3,4, Hui-Wen Yang1,4,5
1School of Pharmacy, National Defense Medical Center, Taipei, Taiwan.
Clinical and experimental dermatology
|July 16, 2024
概括
台湾妇女在怀孕期间使用银病药物的数量显著下降,许多妇女在产前和产后两年内停止治疗. 需要进一步研究对母亲和儿童健康的影响.
科学领域:
- 皮肤病学 皮肤病学
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 牛皮影响全球的2-4%,在生育年龄的妇女中显著流行.
- 怀孕使得牛皮管理复杂化,原因是荷尔蒙的变化和治疗的安全性问题.
- 关于怀孕期间牛皮治疗模式的现实世界数据有限.
研究的目的:
- 通过使用现实世界的数据,调查患有牛皮的孕妇的药物使用情况.
- 为了分析台湾全国一群患者的治疗模式.
主要方法:
- 利用台湾国家健康保险 (NHI) 数据库和出生证明记录 (2005-2014).
- 追踪了孕妇患牛皮的药物使用情况,从怀孕前3年到分娩后3年.
- 按解剖治疗化学代码对药物进行分类,并进行统计分析.
主要成果:
- 研究了30267名患有牛皮的孕妇;38.5%接受了处方.
- 局部皮质类固醇是最常见的,其次是光疗;系统和生物的使用是有限的.
- 药物使用在怀孕期间减少,在第三个三个月达到最低,然后在分娩后增加.
结论:
- 牛皮的治疗 (全身,生物,局部) 在怀孕期间很大程度上被停止,通常是几年前开始和产后继续.
- 这些治疗模式对母亲和儿童健康的影响需要进一步研究.
相关概念视频
01:23Antidepressant Drugs: MAOIs and Other Agents
209
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
209
01:28Drug Therapy
41
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
41
01:23Nonlinear Pharmacokinetics: Dependence of Elimination Half-Life and Dose Clearance
115
The elimination half-life and drug clearance of drugs following nonlinear kinetics can vary with dosage. The Michaelis-Menten parameters and drug concentration influence these factors. As the dose increases, the elimination half-life tends to lengthen, resulting in a reduction in clearance and a disproportionately larger area under the curve. The total clearance can be derived from the Michaelis-Menten equation for drugs following a one-compartment model.
A study on guinea pigs examined the...
A study on guinea pigs examined the...
115
01:23Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
267
Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
267
01:21Factors Affecting Drug Response: Overview
1.9K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
1.9K