过氧化和 hialuronic 酸在第三提取后的口水中的作用:一个三重盲并行随机控制的临床试验
E Boccalari1, S Khijmatgar, C Occhipinti
1Department of Biomedical, Surgical, and Dental Science, University of Milan, Milan, Italy. gianluca.tartaglia@unimi.it.
European review for medical and pharmacological sciences
|July 16, 2024
概括
过氧化 (H2O2) 和酸 (HA) 口水在第三手术后显著改善了口的愈合. 与安慰剂相比,这种组合减少了疼痛和炎症,显示了术后护理的前景.
科学领域:
- 在口腔外科手术中.
- 生物材料科学是生物材料的科学.
- 伤口愈合 伤口愈合
背景情况:
- 第三手术往往会导致术后并发症.
- 生物材料正在被探索,以提高插座愈合.
- 过氧化 (H2O2) 和氨酸 (HA) 组合是一种新的配方用于研究.
研究的目的:
- 评价过氧化 (H2O2) 和酸 (HA) 口水在第三提取后促进口愈合的有效性.
- 为了比较H2O2和HA配方与安慰剂和赫西丁口水.
主要方法:
- 这是一项双盲,并行随机控制的临床试验,涉及114名接受第三牙提取的患者.
- 患者被分为三个组:H2O2和HA,安慰剂或0.2%的氧化.
- 结果包括疼痛,炎症,胀和7天的随访期间的各种愈合参数.
主要成果:
- 所有114名患者完成了这项研究,没有学.
- 与安慰剂组相比,H2O2和HA组显示疼痛 (VAS) 和其他愈合参数的统计显著减少 (p<0.001).
- 该配方证明了对口愈合的积极影响.
结论:
- 该H2O2和HA口水配方显示了第三手术后口愈的潜在好处.
- 建议进行进一步的临床试验,以确认其有效性和临床实用性.
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