政策变化对晚期堕胎的影响:二十年的分析
Marina Pekar-Zlotin1, Yael Nehama-Berman2, Yaakov Melcer2
1Department of Obstetrics and Gynecology, Faculty of Medical and Health Sciences, The Yitzhak Shamir Medical Center (Formerly Assaf Harofeh Medical Center), affiliated with the School of Medicine, Tel Aviv University, Zerifin, Tel Aviv, Israel. pekarm85@gmail.com.
Archives of gynecology and obstetrics
|July 16, 2024
概括
在2007年以色列更新其LTOP政策后,妊娠迟终 (LTOP) 率大幅下降. 基因检测和超声波的进步可能有助于更早的检测,并且在24周后需要LTOP的病例更少.
科学领域:
- 医学伦理 医学伦理
- 生殖医学 生殖医学
- 产前诊断 在产前诊断
背景情况:
- 晚期终止怀孕 (LTOP) 受超声波和分子遗传学的进步的影响.
- 在全球范围内,围绕LTOP的伦理辩论正在进行中.
- 以色列于2007年修订了LTOP政策,设定了LTOP在怀孕24周后出现严重障碍的概率为30%的门.
研究的目的:
- 为了比较LTOP在2007年以色列政策变化之前和之后的指示和批准率.
- 分析1998年至2021年LTOP的趋势.
主要方法:
- 这是一项回顾性研究,分析了1998年1月1日至2021年12月31日期间4047次堕胎的医疗记录.
- 鉴定了248例LTOP在怀孕24周后进行.
- 两个组之间的数据比较,包括母亲的年龄,产科史,指示,诊断,终止妊娠周和遗传/声谱发现:1998-2007年 (第一组) 和2008-2021年 (第二组).
主要成果:
- LTOP病例从第一组的10.6% (95例) 减少到第二组的4.9% (153例).
- 在这两组 (67.4%和65.3%) 中,胎儿结构异常仍然是LTOP的主要指示.
- 确定的遗传异常略有增加,从第一组的26.3%增加到第二组的28%.
结论:
- 在政策更新后,LTOP的年份比例显著下降.
- 基因评估和超声波技术的技术进步可能改善了早期检测,减少了24周后LTOP的需要.
- 强调道德审查和严格的协议对于早期检测和在怀孕24周之前终止的重要性.
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