大型抑郁症中互白素-23/Th17轴的激活:系统性审查和元分析

Calum D Moulton1,2,3, Mantas Malys4, Christopher W P Hopkins5

  • 1Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, SE5 8AF, UK. calum.moulton@kcl.ac.uk.

概括

重度抑郁症与增加的17A (IL-17A) 和粒细胞巨细胞殖民地刺激因子 (GM-CSF) 水平有关. 这表明,联素-23/Th17通路在抑郁症中过度活跃,可能是治疗的目标.

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