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Updated: Jun 21, 2025

Investigation of Genetic Dependencies Using CRISPR-Cas9-based Competition Assays
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Published on: January 7, 2019

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过度表达REC8诱导异常的配体介质分裂,并有助于AML的发病 - 多重微阵列分析和门德尔随机化研究

Wenxi Hua1,2, Jiaqian Qi1,2,3, Meng Zhou1,2,3

  • 1National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.

Annals of hematology
|July 16, 2024
PubMed
概括

这项研究通过分析基因表达和遗传数据来确定急性髓性白血病 (AML) 的潜在治疗点. 它强调REC8是白血病发生的潜在驱动因素,为白血病治疗提供了新的见解.

关键词:
在AML,AML就是AML.门德尔的随机化微阵列分析分析在 REC8 中使用.

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