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炎症性肠病中的微量营养素缺乏:发生率分析
Amir Y Kamel1, Zachary D Johnson1, Isabela Hernandez2
1Department of Pharmacy, UF Health Shands Hospital.
微量营养素缺乏在炎症性肠病 (IBD) 患者中很常见. 铜,维生素A,E和K缺乏经常被忽视,需要提高IBD护理的意识和评估.
科学领域:
- 胃肠病学和肝病学
- 营养科学 营养科学
- 内部医学 内部医学
背景情况:
- 炎症性肠病 (IBD) 患者面临营养不良和微量营养素缺乏,导致诸如贫血,凝血病,伤口愈合不良和结直肠癌风险增加等并发症.
- 识别和解决这些缺陷对于改善患者的结果和预防严重的健康问题至关重要.
研究的目的:
- 在IBD患者中调查特定微量营养素 (铜,维生素A,B9,E和K) 缺乏的患病率.
- 确定与这些微量营养素缺乏相关的常见症状和历史特征,以协助其临床识别.
主要方法:
- 一个回顾性电子图表审查的成年患者诊断出克罗恩氏病或性结肠炎住院治疗IBD爆发.
- 纳入标准涉及有可用血清或全血微量营养素水平的患者; 怀孕和被监禁的人被排除在外.
- 从2013年1月到2017年6月在第三级护理中心收集的数据.
主要成果:
- 在611名IBD患者中,微量营养素水平被分为以下子集评估:铜 (12.3%),维生素A (10.1%),B9 (95.9%),E (10.3%) 和K (4.6%).
- 总体而言,10.1%的患者表现出微量营养素缺乏. 具体缺陷因IBD类型而异,铜,维生素A,E和K的显著率.
- 常见的相关症状包括贫血,肌肉衰弱,疲劳,腹,皮肤干燥,出血和骨质疏松症,这取决于具体的营养缺乏.
结论:
- 微量营养素缺乏在IBD患者中很普遍,但经常被低估.
- 在这个人群中,铜,维生素A,E和K的缺乏特别不被认可.
- 基于相关症状的临床怀疑应促使针对这些缺陷进行有针对性的评估和治疗.
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