儿科瘤学环境中的早期发病精神病:一个病例报告
Yvette Humphrey1, Andrew Elliott2, Arshia Madni3
1Center of Advanced Practice, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Issues in mental health nursing
|July 16, 2024
概括
本案例研究检查了两名患有白血病的青少年男性和同时出现的精神疾病,精神分裂症 (SCZ) 和精神分裂情绪障碍 (SHZ). 它强调了在癌症治疗期间管理这些双重诊断的复杂挑战.
科学领域:
- 精神病学是一个精神病学.
- 在瘤学瘤学.
- 青少年医学 青少年医学
背景情况:
- 精神分裂症 (SCZ) 和精神分裂情绪障碍 (SHZ) 是一种严重的心理健康状况,通常在青春晚期或成年早期出现.
- 虽然这些疾病中经常出现并发症,但与常见的青少年癌症白血病的同时发生尤为罕见,以前没有被描述.
- 精神疾病和癌症治疗之间的相互作用可以显著复杂患者的护理和预后.
研究的目的:
- 介绍两名被诊断患有白血病和同时出现精神疾病的青少年男性的案例研究.
- 概述这些复杂病例的临床表现,病程和治疗反应.
- 探索白血病和精神疾病的同时管理所带来的独特挑战.
主要方法:
- 本研究采用案例研究方法,遵循罗伯特·E·斯泰克的方法.
- 它侧重于两名17岁的男性患者,他们患有白血病和同时出现的精神疾病.
- 数据收集包括临床表现,疾病进展和精神病和瘤病的治疗结果.
主要成果:
- 第一个患者在白血病治疗期间出现了SCZ,而第二个患者在白血病发作之前被诊断出SHZ.
- 这两个案例都说明了精神疾病对白血病治疗的坚持和管理的重大影响.
- 该研究详细介绍了在管理这些双重诊断时遇到的具体挑战.
结论:
- 青少年中白血病和精神疾病的同时发生,带来了独特而复杂的临床挑战.
- 早期发现和综合治疗对于改善这两种情况的结果至关重要.
- 需要进一步的研究来了解和解决这种患者群体的特定需求.
相关概念视频
Treatment Resistant Cancers
2.6K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
2.6K
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
967
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
967
Pharmacokinetics in Pediatric Patients: Drug Distribution
554
Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
554
Pharmacokinetics in Pediatric Patients: Drug Metabolism
410
In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
410
Pharmacokinetics in Pediatric Patients: Drug Excretion
408
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
408
Psychological and Sociocultural Causes of Schizophrenia
977
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
977


