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成年期肥胖症会影响心脏结构和功能在晚年生活中.

Lamia Al Saikhan1, Nish Chaturvedi2, Arjun K Ghosh3,4

  • 1Department of Cardiac Technology, College of Applied Medial Sciences, Imam Abdulrahman Bin Faisal University, 2835 King Faisal Street, Dammam 34212, Saudi Arabia.

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在整个成年期,更高的体重指数 (BMI) 和腰比 (WHR) 与较差的心脏结构和功能有关. 这些对心脏健康的不良影响,即使考虑到晚年肥胖,也会持续存在.

关键词:
肥胖的增加增加了脂肪.成年人的生活过程.心脏功能是什么心脏功能心脏结构的心脏结构静脉缩功能 LV 静脉缩功能大小 LV 质量 LV质量肥胖问题 肥胖问题

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科学领域:

  • 心脏病学 心脏病学
  • 公共卫生 公共卫生
  • 老年学是一门学科.

背景情况:

  • 过度肥胖是心脏功能障碍和左心室 (LV) 重塑的已知危险因素.
  • 成年人肥胖对心脏结构和功能在整个生命过程中的长期影响仍然不清楚.

研究的目的:

  • 调查成人肥胖 (BMI和WHR) 与60-64岁的心脏结构和功能之间的联系.
  • 确定这些关联是否独立于晚年肥胖.

主要方法:

  • 利用了来自1690名国家健康与发展调查出生队列参与者的数据.
  • 身体质量指数 (BMI) 和腰比 (WHR) 的重复测量在整个成年期收集.
  • 心声学评估左心室 (LV) 质量,相对壁的厚度, LV 内部直径在透析,透析功能 (E/e', e',左心房体积),和静脉功能 (排气分数,S',心肌收缩分数) 在60-64岁.
  • 多变量线性回归模型被用来分析关系,调整混因素.

主要成果:

  • 20岁以后的BMI增加与更大的LV质量和LV内部直径有关,独立于混因素.
  • 腹痛中BMI和LV内部直径之间的关联与当前BMI保持独立;LV质量关联在26岁,43岁和53岁时独立于BMI持续存在.
  • 20岁以后的较高BMI与较差的透析功能和左心脏体积增加有关,独立于混因素,在60-64岁的BMI调整后,从26岁持续到26岁.
  • 一些缩功能关联与60-64岁的BMI并不独立.

结论:

  • 整个成年期的脂肪增加与心脏结构和功能的不良影响有关.
  • 特定的心脏变化,特别是左心房体积,在以后的生活中表现为持久性,独立于肥胖.