产前内分泌干扰化学物质暴露和对后代神经发育的影响:系统性审查和元分析
Ziyi Yang1, Jie Zhang2, Mingbo Wang1
1School of Nursing and Rehabilitation, Nantong University, Nantong, Jiangsu, China.
Neurotoxicology
|July 16, 2024
概括
产前暴露于内分泌干扰化学物质 (EDC) 对儿童的神经行为产生负面影响,影响认知,运动技能和语言. 某些特定的化学物质,如金属和甲酸盐,显示出显著的不良关联,其中一些认知效应因性别而异.
科学领域:
- 环境健康 环境健康
- 发育神经科学的发展神经科学.
- 毒理学 毒理学 毒理学
背景情况:
- 已知内分泌干扰化学物质 (EDC) 影响胎儿发育.
- 了解产前EDC暴露对后代神经发育的影响对于公共卫生至关重要.
- 本综述侧重于怀孕期间母亲暴露于EDC与儿童神经发育结果之间的相关性.
结论:
- 产前接触EDC,包括金属,酸盐和PFAS,会扰乱后代的神经行为发育.
- 在短期和长期神经发育结果中观察到不良影响.
- 在产前EDC暴露后,认知发育的性别特异性差异被观察到.
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