相关实验视频

Updated: Aug 10, 2026

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Published on: March 23, 2011

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在死后小鼠大脑组织中使用FASS-LTP来评估病态突触功能

Joshua Currie1, Shaneilahi Budhwani2, Klarissa H Garza3

  • 1John Sealy School of Medicine, University of Texas Medical Branch at Galveston, USA; Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University of Texas Medical Branch, USA.

Journal of neuroscience methods
|July 16, 2024
PubMed
概括

这项研究增强了光辅助单突触长期增强 (FASS-LTP) 方法,用于评估冷脑组织中的突触完整性. 改进的技术为神经退行研究和潜在的临床应用提供了强大的,可重现的分析.

关键词:
这就是FASS-LTP.流动细胞计量流动细胞计量冷的大脑组织.葡萄糖质突触的突触是什么?高吞吐率的高吞吐量.突触神经传递的突触神经传递.

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相关概念视频

Long-term Potentiation01:35

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.