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在现场形成PLA和PLGA植入物,用于对肠道注射大麻素

Irene Lozza1, Cristina Martín-Sabroso2, Ana Isabel Torres-Suárez2

  • 1Department of Pharmaceutics and Food Technology, Faculty of Pharmacy, Complutense University of Madrid, Spain.

International journal of pharmaceutics
|July 16, 2024
PubMed
概括

这项研究开发了用于持续提供大麻素 (CBD) 的新型现场形成植入物 (ISFI). 这些可生物降解的植入物为长期的癌症治疗提供了一个有希望的,无毒的策略.

关键词:
血管新生的产生.在CAM模型中使用CAM模型.大麻素是一种大麻素.药物输送是药物输送的过程.在位置形成植入物植入物.聚合物配方中的聚合物配方.

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The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
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Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...