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对头癌老年患者进行适当的放射治疗利用基准的评估

P Mackenzie¹, C Vajdic², G Delaney³

¹FRANZCR, Royal Brisbane and Women's Hospital, University of QLD, Collaboration for Cancer Outcomes Research and Evaluation (CCORE), The University of New South Wales, Sydney, Australia.

Clinical oncology (Royal College of Radiologists (Great Britain))

|July 16, 2024

概括

80岁以上头癌患者的放射治疗利用率低于最佳水平,尽管与年轻患者相比,治疗完成率和毒性率相似. 这项研究强调了老年人护理方面的差异.

科学领域:

在瘤学瘤学.
辐射瘤学辐射瘤学
老年医学老年医学

背景情况:

头部和部癌症不成比例地影响老年人,一个经常面临治疗复杂性的人口.
在这个人口群体中,放射治疗利用率 (RTU) 需要仔细评估,以确保提供最佳护理.
了解年龄和并发症调整后的RTU对于公平的癌症治疗至关重要.

研究的目的:

确定按年龄分层的头癌患者的实际放射治疗利用率 (RTU).
开发一个最佳的RTU模型,根据年龄和并发性疾病进行调整.
评估老年头癌患者的治疗耐受性和毒性.

主要方法:

使用新南威尔士癌症注册表和放射治疗数据 (2008-2015年) 的回顾性队列研究.
按年龄组计算实际RTU (在诊断后一年内接受放射治疗的比例).
开发了年龄和并发性疾病调整的最佳RTU模型;评估了放射治疗剂量,完成率和急诊室毒性陈述.

主要成果:

在5966名头癌患者中,13.6%的患者年龄在80岁以上.
所有年龄组的实际RTU都低于最佳RTU.
对于80岁以上的患者,最佳RTU为52% (实际40%),治疗性70Gray (Gy) 放射治疗完成92%和与年轻群体相似的急诊室呈现率.

结论:

事实上,80岁以上的头癌患者和所有年龄组的头癌患者的放射治疗利用率都不够理想.
较少的老年患者接受治疗目的放射治疗,尽管治疗完成和急性毒性相似.
这表明,在老年头癌患者中,放射治疗可能未得到充分利用.

关键词:

老年瘤学老年瘤学头部和部癌症头部和部癌症辐射疗法利用的辐射疗法

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