重症病患者在重症监护病房中获得的弱点的风险预测模型:系统性审查
Yue Zhou1, YuJian Sun1, YuFan Pan1
1College of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
概括
对于重症监护室 (ICU) 获得的弱点 (ICU-AW) 的风险预测模型有希望,但需要优化. 进一步验证和高质量的模型开发对于临床应用至关重要.
科学领域:
- 关键护理医学 关键护理医学
- 临床流行病学临床流行病学
- 医疗信息学 医疗信息学
背景情况:
- 在重症监护室 (ICU) 获得的虚弱 (ICU-AW) 是影响患者预后的重大并发症.
- 风险预测模型被认为是指导ICU-AW预防干预的有价值的工具.
- 现有的ICU-AW风险预测模型的临床质量和适用性尚未得到充分证实.
研究的目的:
- 系统地审查和评估ICU-AW发布的风险预测模型.
- 评估这些模型在临床实践中的质量,偏差和适用性.
主要方法:
- 从创立到2023年10月,在多个电子数据库中进行全面的文献搜索.
- 两名独立研究人员对文章进行选,提取数据,并严格评估偏差风险和模型适用性.
- 对ICU-AW.的确定的风险预测模型的分析.
主要成果:
- 从2709篇最初查的文章中,确定了25个ICU-AW风险预测模型.
- 模型显示了广泛的区分能力 (AUC 0.6810.926),其中十个验证模型显示了0.83.3的AUC.
- 所有模型都表现出高偏差风险,三种模型的适用性不佳;关键预测因素包括机械通风持续时间,年龄和ICU停留时间.
结论:
- 强症监护室-AW风险预测模型具有有前途的区分能力.
- 数据异质性,研究设计偏见和统计验证不足等局限性需要模型优化.
- 未来的研究应该专注于外部验证和开发高质量的预测模型,以提高临床效用.
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