在结直肠癌查人群中,与分泌瘤相关的细分性结肠炎 (SCAD):患病率,内镜特征和瘤结局
Nicola Imperatore1, Gabriella Cordone1, Luigi Martorelli1
1Gastroenterology and Endoscopy Unit, P.O. Santa Maria delle Grazie, Pozzuoli, Naples, Italy.
与分泌突症相关的细分性结肠炎 (SCAD) 影响4.5%的接受结肠镜检查的患者. 与简单的转结病相比,SCAD与腺瘤和结直肠癌 (CRC) 的发病率较低有关.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠癌查 结肠直肠癌查
- 炎症性肠道疾病 炎症性肠病
背景情况:
- 细分性结肠炎与分泌腺炎相关 (SCAD) 是一种慢性炎症状况,影响分泌腺之间的结肠粘膜.
- SCAD特别省略了直肠和右结肠,使其与其他大肠炎类型区别开来.
研究的目的:
- 在结直肠癌 (CRC) 查计划中确定SCAD的患病率.
- 为了比较SCAD患者和没有并发症的分泌瘤患者之间的瘤结果.
主要方法:
- 使用从前性维护的数据库中获取的数据进行了回顾性分析,该数据库包含了接受首次查结肠镜检查的患者.
- 1518名患者被纳入分析.
主要成果:
- 在4.5%的患者中诊断出SCAD,在37.5%的患者中诊断出分.
- 与没有并发症的分泌腺瘤患者相比,SCAD患者的腺瘤检测率明显较低 (31.9%与47.3%,p=0.018).
- 在SCAD患者中观察到较低,但不具有统计学意义的CRC率的趋势 (1.4%对6.2%,p=0.14).
结论:
- 在接受查结肠镜检查的个体中,SCAD可在约5%的个体中识别出来,而在患有分泌腺炎的个体中,SCAD可在12%的个体中识别出来.
- 与分泌瘤相比,SCAD似乎与腺瘤和潜在的结直肠癌的发病率降低有关.
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