与纳税人相关的跌倒风险:关注化疗诱导的外周神经病变
Constance Visovsky1, Patricia Teran Wodzinski1, Douglas Haladay1
1University of South Florida, Tampa, FL.
Seminars in oncology nursing
|July 16, 2024
概括
患有乳腺癌的妇女经历化疗诱导的周围神经病变 (CIPN) 面临严重的跌倒风险. 接近跌倒和脚力量降低是关键预测因素,突出了针对性干预的必要性.
科学领域:
- 在瘤学瘤学.
- 神经学 神经学
- 老年学是一门学科.
背景情况:
- 化疗诱导的周围神经病变 (CIPN) 是基于税的化疗在乳腺癌患者的常见和衰弱的副作用.
- 持续的CIPN可能导致步态,平衡和力量受损,增加跌倒和随后受伤的风险.
- 了解基线跌倒风险因素对于在这个脆弱人群中制定有效的预防策略至关重要.
研究的目的:
- 为了确定基线跌倒风险,在接受基于税的化疗的持久性CIPN的女性中.
- 在这个患者群体中确定未来跌倒的显著预测因素.
主要方法:
- 从一项随机临床试验中对62名患有持续性CIPN的参与者进行了前性分析.
- 收集了基线人口统计,医学,神经传导,步态,平衡和肌肉力量数据.
- 使用拉索的通用线性建模用于识别未来跌倒的重大风险因素.
主要成果:
- 在过去一个月内近距离跌倒 (OR=2.46) 和右脚足底屈曲扭矩减少 (OR=1.05) 与未来跌倒有显著的相关性.
- 人口统计数据,神经传导,步态,平衡和整体肌肉力量并不能显著预测跌倒风险.
- 干预组和对照组之间没有观察到基线特征的显著差异.
结论:
- 接近跌倒和脚强度是评估乳腺癌幸存者的跌倒风险的关键因素,但经常被忽视,CIPN.
- 瘤学临床医生,特别是护士,应该经常询问近距离跌倒情况,并考虑推物理治疗以解决下肢弱点.
- 需要进一步的研究来开发和评估以证据为基础的干预措施,以减轻跌倒风险并改善CIPN患者的功能结果.
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