在脊柱病理学中使用扩散张力成像:全面的文献综述
Tyler Scullen1,2, James Milburn3, Kevin Aria4,5
1Department of Neurological Surgery, Ochsner Clinic Foundation, 1514 Jefferson Hwy, Jefferson, LA, 70112, USA. tylerscullen@gmail.com.
概括
脊柱扩散张力成像 (sDTI) 有助于手术决策和对各种脊柱病理的结果评估. 需要进一步的前性研究来确认其在临床预后中的有用性.
科学领域:
- 神经外科 神经外科
- 放射学 放射学是一门学科.
- 脊髓成像 脊髓成像
背景情况:
- 脊髓扩散张力成像 (sDTI) 评估关键神经通路的完整性.
- sDTI提供了关于脊髓长段功能状态的宝贵见解.
- 它可以作为一种潜在的工具来帮助管理脊髓疾病.
研究的目的:
- 系统地审查当前关于脊柱扩散张力成像 (sDTI) 在管理脊柱疾病中的应用文献.
- 评估在手术相关的脊柱病理中SDTI的诊断和预后价值.
主要方法:
- 按照PRISMA指南进行了系统的文献审查,但不包括纯计算研究和非手术应用.
- 研究包括了手术可接受的脊髓病理,经历SDTI的人类受试者.
- 排除标准侧重于非临床数据,头骨DTI,以及缺乏客观实验或临床数据的研究.
主要成果:
- 文学专注于退行性疾病,如宫骨髓病 (75.9%) 和腰椎脊椎病 (24.1%).
- 研究 sDTI 检查了腹腔内占据质量的病变,重点是手术前和手术内成像 (分别为 77.8% 和 22.2%).
- 在创伤性脊髓损伤中,SDTI被用于预后和严重程度分级.
结论:
- 脊柱扩散张力成像 (sDTI) 在手术决策,结果评估和跨多种脊柱病理的临床预后中表现出实用性.
- 建议进一步进行高质量的研究,使用前性,受控的方案,更大的队列和延长的随访.
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