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Updated: Jun 21, 2025

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准CCL2-CCR2信号通路可通过PI3K-AKT轴缓解COPD中巨细胞功能障碍

Yue Dong1,2,3,4, Ying Dong4, Chengyue Zhu1,2,3

  • 1Department of Respiratory and Critical Care Medicine, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.

Cell communication and signaling : CCS
|July 16, 2024
PubMed
概括

通过CCR2受体激活巨细胞,C-C动机化学基因连接体2 (CCL2) 驱动慢性阻塞性肺病 (COPD). 抑制这种途径可以防止肺损伤和气道重塑,为COPD提供潜在的治疗点.

关键词:
支气管上皮细胞是支气管上皮细胞.慢性阻塞性肺病是一种慢性阻塞性肺病.CC 化学因子受体2型CC动图的化学基因连接体2 2巨细胞是一个巨细胞.

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