美国门诊和急性不补偿性心力衰竭注册表 (AMERICCAASS注册表):理由和设计
Juan Esteban Gómez-Mesa1,2,3,4, Juliana María Gutiérrez-Posso2, Manuela Escalante-Forero2
1Department of Cardiology, Fundación Valle del Lili, Cali, Colombia.
ESC heart failure
|July 17, 2024
概括
美国卡萨斯注册表将对整个美洲的心力衰竭 (HF) 患者进行表征,以改善治疗. 这项研究旨在了解高风的人口统计,并发症和结果,以告知公共卫生政策.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 临床研究 临床研究
背景情况:
- 心力衰竭 (HF) 是一种流行,渐进的疾病,患病率和死亡率很高.
- 急性失补偿性HF每年导致数百万人住院治疗,但预后仍然很差.
- 对于拉丁美洲和加勒比地区的数据有限,这阻碍了对特定地区的理解和治疗优化.
研究的目的:
- 在美洲大陆特征出 ambulatory 和急性失补偿 HF 的人口.
- 为了确定12个月的随访期间的再住院和生存结果.
- 解决高频研究中的特定区域差距,并为公共卫生政策提供信息.
主要方法:
- 在美洲至少20个国家的观察性,前性,基于医院的注册表 (AMERICCAASS注册表).
- 包括门诊和急性失补偿的HF患者,在出院1,6和12个月后进行随访,或从门诊患者的基线开始.
- 通过REDCap收集的数据,使用统计分析,包括t测试,非参数测试,费舍尔精确测试和卡普兰-梅尔生存分析.
主要成果:
- 目前AMERICCAASS注册正在进行中,招聘将于2023年11月结束,后续调查将于2025年1月结束.
- 数据收集使用REDCap进行人口统计,病因学,并发症和治疗的公正分析.
- 现有统计方法用于量化和分类变量比较,包括生存分析.
结论:
- 美国电磁场注册表即将成为了解美洲各地高频的关键资源.
- 它将提供有关HF人口统计,病因学,并发病症和治疗模式的基本数据.
- 预计这些发现将有助于优化基于证据的国家和区域公共政策,以诊断和管理HF.
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