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Updated: Jul 20, 2026

Au-Interaction of Slp1 Polymers and Monolayer from Lysinibacillus sphaericus JG-B53 - QCM-D, ICP-MS and AFM as Tools for Biomolecule-metal Studies
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Au-Interaction of Slp1 Polymers and Monolayer from Lysinibacillus sphaericus JG-B53 - QCM-D, ICP-MS and AFM as Tools for Biomolecule-metal Studies

Published on: January 19, 2016

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通过多光谱方法与分子动力学相结合,探测金属β-乳糖酶SMB-1和安培素之间的相互作用

Jiachen Li1, Xiaoting Dong2, Yeli Zhang1

  • 1College of Biological Sciences and Technology, Taiyuan Normal University, Jinzhong, China.

Journal of molecular recognition : JMR
|July 17, 2024
PubMed
概括

像SMB-1一样的金属β-乳酸酶 (MβLs) 禁用抗生素. 了解SMB-1如何与安培 (AMP) 相互作用,揭示了设计抗药性细菌新药的机制.

关键词:
来自塞拉蒂亚的SMB‐1在市场上获得了优势.氨基氨酸是什么 氨基素是什么光光谱的光谱分子动力学分子动力学分子识别分子识别

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The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions08:06

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions

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Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...