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Updated: Jun 21, 2025

Automated Hydrophobic Interaction Chromatography Column Selection for Use in Protein Purification
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基于紫外线的动态控制提高了多列逆流溶剂梯度净化寡核酸的稳定性

Ismaele Fioretti1, Thomas Müller-Späth2, Lars Aumann2

  • 1Department of Chemistry, Materials and Chemical Engineering, Politecnico di Milano, Milano, Italy.

Biotechnology journal
|July 17, 2024
PubMed
概括

基于UV的动态控制增强了用于治疗性寡核酸 (ON) 制造的多列反流溶剂梯度净化 (MCSGP). 这提高了工艺的稳定性和稳定性,克服了大规模ON生产的挑战.

关键词:
自动峰值 (AutoPeak) 是一个自动峰值.我们的MCSGP染色体学 染色体学 染色体学连续色谱学 连续色谱学反流动的反流动的情况.动态过程控制 动态过程控制氧核酸类的部分.模拟移动床的模拟移动床

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