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在符合PREP资格的MSM中识别性行为模式和PrEP吸收特征:一项全国横截面研究
Yuanyuan Liu1, Xuan Liu1, Siyue Wei1
1Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.
Journal of virus eradication
|July 17, 2024
概括
了解与男性发生性关系的男性 (MSM) 的性行为是增加暴露前预防 (PrEP) 吸收的关键. 识别明显的风险模式有助于定制干预措施,以促进PrEP使用并降低艾滋病毒风险.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 行为科学 行为科学
背景情况:
- 与男性发生性关系的男性 (MSM) 不成比例地受到艾滋病毒的影响.
- 暴露前预防 (PrEP) 是一种有效的艾滋病毒预防工具,但符合条件的MSM的吸收率仍然不够理想.
- 了解性行为的复杂相互作用对于改善PrEP可访问性和遵守性至关重要.
研究的目的:
- 在中国大陆有资格接受PrEP的MSM中识别明显的性行为模式.
- 检查在已识别的性行为模式中的人口变化和PrEP吸收情况.
- 为提高PrEP吸收率和艾滋病毒预防策略提供有针对性的干预信息.
主要方法:
- 隐性类分析 (LCA) 用于对性行为模式进行分类.
- 在中国大陆招募了5877名16岁以上的MSM,符合PrEP资格标准的样本.
- 奇平方测试和多项逻辑回归分析了人口差异和prep吸收.
主要成果:
- 确定了三个不同的性行为模式:低风险 (4,815),中等风险 (516) 和高风险 (546).
- 年龄较大 (≥25岁) 和收入较高 (≥8,000日元/月) 与中等风险组相关.
- 艾滋病毒发病率较高的地区和接受性交 ("顶部") 与中高风险组有关.
- 与低风险组相比,中高风险组表现出明显更高的prep意愿,吸收和坚持.
结论:
- 隐性类分析有效地识别了MSM群体中多样化的性行为模式.
- 基于已识别的风险模式的有针对性的干预措施可以增强PrEP的吸收和坚持.
- 解决人口差异和针对特定风险群体量身定制战略对于有效传播PrEP和在符合条件的MSM中减少艾滋病毒风险至关重要.
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