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肥胖对不同牙周状况的受试者下菌群组成的影响:系统性审查
Mario Alberto Alarcón-Sánchez1
1Department of Research in Microbiology, Faculty of Chemical and Biological Sciences, Autonomous University of Guerrero, Chilpancingo 39090. Guerrero, Mexico. marioaasanchez@hotmail.com Department of Research in Microbiology Faculty of Chemical and Biological Sciences Autonomous University of Guerrero Chilpancingo 39090. Guerrero Mexico marioaasanchez@hotmail.com.
概括
肥胖与下微生物群的显著变化有关,经常检测到牙周病原体. 进一步的研究可以建立微生物组分析,以改善肥胖和牙周病的管理.
科学领域:
- 口腔微生物学 口腔微生物学
- 牙周病学 牙周病学
- 肥胖研究的研究.
背景情况:
- 肥胖是一个日益严重的全球健康问题.
- 牙周病很普遍,与全身健康有关.
- 肥胖和口腔微生物群组成之间的关系需要进一步研究.
研究的目的:
- 系统地审查不同体重状况 (正常,超重,肥胖) 和牙周健康/疾病的个体的牙下微生物群组成的变化.
- 确定与肥胖和牙周炎相关的特定微生物模式.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 在PubMed/MedLine,Scopus和Web of Science进行的搜索.
- 包括观察性研究,分析肥胖 (BMI>30kg/m2),牙炎或牙周炎的受试者的下微生物群.
主要成果:
- 对1229名受试者 (894名暴露者,335名对照者) 下微生物群的分析.
- 牙周病原体如*Porphyromonas gingivalis*,*Tannerella forsythia*和*Fusobacterium nucleatum*在肥胖和牙周炎的受试者中普遍存在.
- 还确定了诸如*Streptococcus gordonii*和*Veillonella parvula*等辅助病原体,这些病原体可能会增强毒性.
结论:
- 在肥胖和牙周炎的个体中,下微生物组合的显著变化是明显的.
- 确定肥胖的特定微生物特征仍然具有挑战性.
- 下微生物和肥胖之间确定的关联可以加强肥胖的预防策略和管理.
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