患者对通用替代政策的偏好:中国的一个离散选择实验
Lingli Zhang1, Dashuang Li2, Xin Li3,4,5
1School of International Pharmaceutical Business, China Pharmaceutical University, Nanjing, China.
Frontiers in pharmacology
|July 17, 2024
概括
患者对通用替代政策的偏好主要是由通用一致性评估 (GCE) 驱动的. 优化GCE和信息披露可以显著提高患者接受这些药物获取政策的情况.
科学领域:
- 药物经济学 药物经济学
- 医疗保健服务研究 医疗服务研究
- 患者的偏好 患者的偏好
背景情况:
- 通用替代政策旨在提高全球药物可用性.
- 患者对当前通用替代政策的不满需要进一步调查.
- 了解患者的偏好是优化这些政策以获得更好的接受的关键.
研究的目的:
- 评估患者对通用替代政策各种属性的偏好.
- 确定影响患者接受仿制药的关键因素.
- 探索优化策略,以提高患者对仿制药替代品的接受度.
主要方法:
- 使用离散选择实验 (DCE) 来评估五个政策属性的相对重要性.
- 在中国三个城市,对住院和门诊患者进行了面对面的调查.
- 使用混合逻辑模型分析偏好系数,属性重要性和政策采用率.
主要成果:
- 通用一致性评估 (GCE) 是最关键的属性 (RI=56.64%),其次是报销率和信息披露.
- 患者的偏好显示出基于性别和收入的异质性.
- 仅仅改善GCE可以将政策采用率从68.56%提高到82.63%;信息披露也显示出重大影响.
结论:
- 仿制药的一致性评估是患者接受中国仿制药替代政策的主要驱动因素.
- 目前的政策可以通过专注于GCE和信息披露来优化,以减轻负面影响.
- 加强这些方面可以显著提高患者对通用替代方案的接受度和满意度.
相关概念视频
Analysis of Population Pharmacokinetic Data
252
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
252
Prescription, Nonprescription and Orphan Drugs
714
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
714
Crossover Experiments
2.8K
Crossover experiments, also called the repeated-measurements design, is a study design in which all experimental units are exposed to all treatments in different periods. Crossover experiments are generally used in psychology, the pharmaceutical industry, agriculture, and medicine.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
2.8K
Pharmacokinetic Models: Comparison and Selection Criterion
66
Physiological and compartmental models are valuable tools used in studying biological systems. These models rely on differential equations to maintain mass balance within the system, ensuring an accurate representation of the dynamic processes at play.
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.
66
Blind Procedures
10.6K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
10.6K
Drug Nomenclature
1.7K
During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United States Adopted Name (USAN)—a generic, nonproprietary designation. Upon being listed in the United States Pharmacopeia, this nonproprietary name becomes the drug's official name. Additionally, the manufacturer assigns a proprietary name or trademark, which serves as the brand name under which the drug is marketed. It is worth noting that...
1.7K


