皮病Lichenoides et Varioliformis Acuta 在为膀癌治疗Pembrolizumab期间发展
Yuki Mizutani1, Ena Noda1, Makoto Kondo1
1Department of Dermatology, Graduate School of Medicine, Mie University, Tsu, Japan.
Case reports in dermatology
|July 17, 2024
概括
抗PD-1免疫疗法可能会导致皮肤问题. 一个罕见的病例显示,在治疗膀癌的pembrolizumab期间,pityriasis lichenoides et varioliformis acuta (PLEVA) 发生,这表明这些疗法与特定的免疫相关皮肤不良事件之间存在联系.
科学领域:
- 免疫学 免疫学 免疫学
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
背景情况:
- 抗PD-1 免疫疗法,如 pembrolizumab,通过阻断PD-1/PD-L1 相互作用来利用T细胞对抗癌症的反应.
- 这些疗法对各种癌症有效,但可能导致与免疫相关的不良事件 (irAEs),经常影响皮肤.
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