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Transgenic Plants02:50

Transgenic Plants

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Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
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Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products
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采矿原料植物对新型环酸的转录基因数据.

Draco Kriger1, Michael A Pasquale1, Brigitte G Ampolini1

  • 1Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, NC, USA.

Beilstein journal of organic chemistry
|July 17, 2024
PubMed
概括

植物转录组的生物信息分析揭示了burpitide前体的分布. 这一发现有助于通过代谢分析从植物中识别新的环类甲.

科学领域:

  • 自然产品的发现自然产品的发现
  • 生物信息学是一种生物信息学.
  • 植物科学 植物科学

背景情况:

  • 基因组和转录基因组开采加速了微生物中的自然产品发现.
  • 植物天然产品的发现受到有限的基因组数据和不一致的基因聚类的阻碍.
  • 布尔皮提德是一种由核糖体合成和翻译后修饰的 (RiPPs) 的类,由于生物合成途径短,它为生物信息学引导的植物发现提供了机会.

研究的目的:

  • 通过生物信息学方法,研究在Streptophyta中分裂的burpitide前体的潜在分布.
  • 为了识别植物中的新型环类化物.

主要方法:

  • 700个公共转录基因数据集的高通量组装和分析.
  • 生物信息预测burpitide前体的分布.
  • 选择植物物种的代谢分析.

主要成果:

  • 在Streptophyta中发现了分裂的burpitide前体的潜在分布.
  • 通过代谢分析证实了生物信息学预测.
  • 从已知和以前未被描述的植物来源鉴定出新的环类甲.

结论:

关键词:
这就是RiPPs.皮疹是一种皮疹.自然产品是自然产品的产品.植物植物植物植物植物植物.转录组采矿的采矿工作

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  • 生物信息学引导的发现是有效的识别RiPPs,像burpitides,在植物.
  • 这项研究扩大了已知的来源和植物衍生型环类的多样性.
  • 这些发现为进一步探索植物天然产品铺平了道路.