相关实验视频

Updated: Jun 20, 2025

Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development

Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development

Published on: May 17, 2024

婴儿微细胞贫血与注意力缺陷多动障碍之间的关联,一个病例控制研究

Michal Yackobovitch-Gavan^1,2, Daniel Ben-Hefer², Ilan Feldhamer³

¹The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.

|July 17, 2024

概括

婴儿期的微细胞贫血与ADHD相反相关,这意味着ADHD儿童的患病率较低. 这一发现挑战了早期贫血会增加ADHD风险的假设.

科学领域:

儿科血液学儿科血液学
儿童神经学儿童神经学
营养流行病学营养流行病学

背景情况:

由于缺铁而导致的微细胞贫血在儿童中很常见,并与认知缺陷有关.
调查幼儿贫血和注意力缺陷/多动障碍 (ADHD) 之间的联系对于了解发育影响至关重要.

研究的目的:

检查婴儿时期 (9-18个月) 微细胞性贫血与儿童期ADHD随后发展之间的关联.
确定早期缺铁性贫血是否是ADHD的危险因素.

主要方法:

一项涉及6-18岁健康儿童的病例控制研究,通过兴奋剂处方确定了ADHD病例.
对照组根据出生年份,性别和文化背景进行了匹配. 微细胞性贫血是由特定的血红蛋白和MCV水平来定义的.
使用了根据社会经济地位和出生年份进行调整的有条件后勤回归分析.

主要成果:

任何微细胞贫血的患病率在ADHD组 (3.4%) 与对照组 (4.0%) 相比较低,调整后的几率比率为0.86.
中度微细胞性贫血的患病率在各组之间相似 (0.9%对1.0%).
在ADHD组中,在男孩,世俗传统犹太儿童和研究队列中的老年儿童中观察到较低的贫血患病率.

结论:

该研究发现婴儿期微细胞贫血和ADHD之间存在小反向关联,拒绝了最初的假设.
需要进一步的研究来探索铁缺乏,大脑铁度和ADHD发展之间的复杂关系.

关键词:

注意力缺陷多动障碍注意力缺陷多动障碍案例控制研究研究.童年童年童年童年血液中的血球蛋白.微细胞性贫血是什么意思

更多相关视频

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

Published on: June 12, 2020

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Published on: March 12, 2020

相关概念视频

Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....

Human Genetics

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...

Autism Spectrum Disorder

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.