rhesus (Rh) 抗原的分布模式
Babita Raghuwanshi1, Kanchan Ahuja2, Garima Sharma2
1Transfusion Medicine, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Cureus
|July 17, 2024
概括
这项研究评估了扩展的 rhesus (Rh) 抗原的患病率,发现抗原 e 是最常见的,而 E 是最不常见的. 了解Rh抗原频率对于输血药物和预防非免疫接种至关重要.
科学领域:
- 输血医学 输血医学
- 免疫学 免疫学 免疫学
- 遗传学 遗传学是一种遗传学.
背景情况:
- 血型的确定依赖于遗传的红细胞 (RBC) 抗原.
- 在ABO系统之后,扩展的 rhesus (Rh) 抗原在输血医学中至关重要.
研究的目的:
- 通过血清学来评估各种血型中扩展Rh抗原的患病率.
- 为输血实践和免疫预防策略提供信息.
主要方法:
- 使用单克隆抗血清检测了2043个ABO血型和Rh型的样本.
- 在所有样本上进行了C,c,E和e抗原的Rh表型鉴定.
主要成果:
- 血型O是最常见的 (36.5%),AB是最不常见的 (13.6%).
- 在91.6%的样本中,RhD抗原呈阳性.
- 抗原e是最普遍的,其次是D;抗原E是最不常见的.
结论:
- 建立一个Rh型表型存储库有助于血液捐献者管理.
- 在输血之前的常规Rh表型测试可以减少患者的免疫接种.
更多相关视频
07:11Multicolor Flow Cytometry Analyses of Cellular Immune Response in Rhesus Macaques
Published on: April 22, 2010
21.2K
07:26High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment
Published on: July 18, 2017
11.8K
相关概念视频
Rh Blood Group
1.4K
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
1.4K
Blood Types
17.5K
Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
17.5K
Blood Typing
1.2K
Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
1.2K
Blood Transfusion and Agglutination
10.8K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
10.8K
Diversity of Antigen Receptors
562
Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
562
Development of Immunocompetence
300
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
300
