与艾滋病毒感染的中年男性骨肌肉质量相关的因素
Yide Xu1, Dongdong Wang1, Pei Chen1,2
1Department of Nutrition and Food Safety, School of Public Health, Nanjing Medical University, Nanjing, China.
Journal of cachexia, sarcopenia and muscle
|July 17, 2024
概括
低肌肉质量影响7.1%的中年男性感染艾滋病毒. 保护因素包括齐多丁 (AZT) 和较高的白蛋白. 体重指数和营养风险指数有效地预测了这一群体的肌肉损失.
科学领域:
- 老年学是指老年学的学科.
- 传染性疾病 传染性疾病
- 营养科学 营养科学
背景情况:
- 艾滋病毒感染的中年男性 (PLWH) 肌肉损失的患病率和促成因素尚不清楚.
- 这项研究调查了这个特定的人口群体的低肌肉质量.
研究的目的:
- 确定艾滋病毒感染的中年男性肌肉质量低的流行情况.
- 在这个人群中确定与低肌肉质量相关的因素.
主要方法:
- 对378名艾滋病毒感染者进行了评估.
- 低肌肉质量被定义使用骨肌肉指数 (SMI) 标准从亚洲工作组的萨尔科佩尼亚2019年.
主要成果:
- 7.1%的参与者肌肉质量较低.
- 齐多丁 (AZT) 和较高的血清白蛋白水平具有保护作用.
- 体重指数 (BMI) 和营养风险指数 (NRI) 显示出高灵敏度和特异性,用于诊断低肌肉质量.
- 在肌肉质量较低的人群中,高指数明显更为普遍,这表明液体保留.
结论:
- 抗逆转录病毒药物类型 (齐多夫丁),BMI和NRI是艾滋病毒感染男性肌肉质量低的独立危险因素.
- BMI和NRI可以用于方便地预测低肌肉质量.
- edem 指数可以作为 PLWH 低肌肉质量风险的指标.
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