炎症负担和心房动负担:双向关系
Abdulrahman Naser1, Samet Sayilan2, Oya Güven3
1Kırklareli Training and Research Hospital - Department of Cardiology, Kırklareli - Turquia.
Arquivos brasileiros de cardiologia
|July 17, 2024
概括
系统性免疫炎症指数 (SII) 与心房 (AF) 负担有关. 较高的SII可能表明永久AF的可能性更高,这表明其在风险分层中的潜在作用.
科学领域:
- 心脏病学 心脏病学
- 免疫学 免疫学 免疫学
- 生物标志物 生物标志物
背景情况:
- 前庭动 (AF) 的负担,在AF中花费的时间,因类型而异 (阴影性或永久性).
- 炎症在AF的发展和维持中起着重要作用.
- 系统性免疫炎症指数 (SII) 和AF负担之间的关联仍然不清楚.
研究的目的:
- 调查系统性免疫炎症指数 (SII) 和心房 (AF) 负担之间的关系.
- 评估SII在确定AF模式中的预测作用.
主要方法:
- 对453名AF患者的横截面分析 ( Paroxysmal 和永久性).
- SII计算为 (中性粒细胞 × 血小板/淋巴细胞).
- 逻辑回归用于评估SII和其他AF模式的炎症标志物的预测值.
主要成果:
- 永久性AF患者表现出更高的年龄水平,透气血压,心率,糖尿病,中性粒细胞,血小板与淋巴细胞的比率,中性粒细胞与淋巴细胞的比率,SII,C反应蛋白,红细胞分布宽度,血红蛋白A1c和左心脏直径.
- 后勤回归确定了年龄,糖尿病,红细胞分布宽度,C反应蛋白,SII和左心脏直径作为永久性AF的显著预测因素.
结论:
- 系统性免疫炎症指数 (SII) 与心房 (AF) 负担独立相关.
- 需要进一步的前性研究来探索SII在识别AF进展高风险患者中的实用性.
相关概念视频
Imbalances in Cardiac Output
1.4K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.4K
Psychoneuroimmunology: Cardiovascular Disease
30
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
30
The JAK-STAT Signaling Pathway
8.8K
Several cytokine receptors have tightly bound Janus kinase or JAK proteins attached at their cytosolic tail. Small signaling molecules such as cytokines, growth hormones, or prolactins bind to the cytokine receptors and initiate their dimerization. The dimerization brings the cytosolic JAKs together that trans-phosphorylate and activates each other. The activated JAKs now phosphorylate cytosolic tails of the cytokine receptors, which serve as binding sites for adaptor proteins such as SH2...
8.8K
Asthma-III: Symptoms and Complications
2.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.5K
Inflammatory Bowel Disease II: Crohn's Disease
210
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
210
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.7K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.7K


