在治疗阿片类药物使用障碍时服用布普伦诺芬或美沙的患者中进行术后疼痛控制
Aurora Quaye1, Tal Tsafnat2, Janelle M Richard3
1Department of Anesthesiology and Perioperative Medicine, Maine Medical Center, Portland; Division of Anesthesiology, Spectrum Healthcare Partners, South Portland, Maine; Tufts University School of Medicine, Boston, Massachusetts. ORCID: https://orcid.org/0000-0002-7573-2164.
Journal of opioid management
|July 17, 2024
概括
在手术期间继续服用阿片类药物使用障碍 (OUD) 的药物,如布普伦诺芬和美沙,至关重要. 停止使用布普伦诺啡因增加了手术后的阿片类药物使用,突出显示了手术前期OUD药物管理的重要性.
科学领域:
- 麻醉学和疼痛管理
- 成 药物 药物 药物 药物
- 药理学 药理学是指药理学的学科.
背景情况:
- 患有阿片类药物使用障碍 (OUD) 的患者需要在外科期间仔细管理疼痛和阿片类药物.
- 治疗阿片类药物使用障碍 (MOUD) 的药物,包括甲和布普伦诺芬,对于管理OUD至关重要.
- 继续或停止服用这些药物对术后疼痛结果的影响尚未完全理解.
研究的目的:
- 为了比较手术后疼痛得分和阿片类药物消耗,在接受选择性手术的患者中,他们保持在甲和布普伦诺芬的OUD.
- 研究继续或停止服用甲或布普伦诺芬对术后疼痛管理的影响.
主要方法:
- 一项回顾性队列研究在第三级护理医疗中心进行.
- 包括在2017年1月至2021年1月期间接受选择性手术的甲或布普伦诺芬OUD的成年患者 (≥18岁).
- 在手术后72小时内收集和分析了阿片类药物消耗 (毫克吗啡等价物) 和疼痛评分 (数值评分表) 的数据.
主要成果:
- 该研究包括366名患者 (64%服用布普伦诺芬,36%服用甲).
- 当手术后不使用布普伦诺芬时,阿片类药物的利用率显著增加.
- 组间的阿片类药物的总消费量是可比的,但根据手术后的MOUD接收,布普伦诺芬队伍的疼痛评分有显著的差异.
结论:
- 现有证据支持在术后期继续服用甲和布普伦诺芬.
- 手术后停止使用布普伦诺芬与阿片类药物消费增加有关.
- 传播外科手术期间MOUD管理指南对于OUD患者的最佳疼痛控制至关重要.
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