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内静脉推送lacosamide:在整个卫生系统的成功实施和患者的结果
Julie R Spangler1, Sarah Young2, Dustin R Carr2
1Department of Pharmacy, University of Wisconsin Hospitals and Clinics, Madison, WI, USA.
概括
将静脉注射lacosamide从背带到推的转换是可行的,并提高了效率. 这种工作流变化显著减少了给药的时间,而不会影响患者的安全.
科学领域:
- 药理学 药理学是指药理学的学科.
- 临床药房 临床药房
- 卫生系统管理管理卫生系统管理
背景情况:
- 静脉注射lacosamide因使用过期和受控物质法规的短暂而面临延迟.
- 运营挑战影响了关键抗发作药物的及时交付.
研究的目的:
- 描述静脉注射lacosamide从背靠背转向推送的实施过程.
- 证明这种工作流变化可以改善管理时间.
- 确保在整个过渡期间保持患者的安全.
主要方法:
- 一项多中心研究,涉及前性实施描述和后性队列分析.
- 静脉注射背与静脉注射拉科萨米德推送剂量≤400毫克的比较.
- 安全性评估包括一个复合的终点和PR延长发生率.
主要成果:
- 在6个月的时间内成功实现全系统实施.
- 从验证到给药的时间显著减少,从159分钟 (背) 减少到88分钟 (推) (P = 0.008).
- 在施用方法之间没有观察到安全性复合物或PR延长的显著差异.
结论:
- 在大型卫生系统中,将静脉注射lacosamide转换为推送给药是可行的.
- 这种变化有效地减少了施用时间.
- 转向静脉注射的推送给药不会增加不良反应.
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