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Updated: Jun 20, 2025

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系统性炎症增强了异构神经母细胞瘤小鼠模型中的转移性生长

Kazuya Mimura1, Shigehisa Fumino2, Kodai Yamashi2

  • 1Department of Pediatric Surgery, Kyoto Prefectural University of Medicine, 465 Kajii Cho, Kawaramachi Hirokoji, Kamigyo Ku, Kyoto, 602-8566, Japan. kazuyam@koto.kpu-m.ac.jp.

Pediatric surgery international
|July 17, 2024
PubMed
概括

部分切除等手术因素可能会增强神经母细胞瘤的转移生长. 系统性炎症,由C-反应蛋白和互白素-6表示,似乎驱动了这种转移性传播的增加.

关键词:
转基因小鼠 MYCN 转基因小鼠转移 转移 转移 转移神经母细胞瘤是一种神经母细胞瘤.外科手术的炎症发生.合成基因小鼠模型

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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