血压时间在范围和综合性心血管结果之间的关系在患有原发性阿尔多斯特主义的患者:一个回顾性案例研究
Fangfang Yan1, Huangdao Yu2, Liping Lan3
1Department of Endocrinology and Diabetes, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Endocrine
|July 17, 2024
概括
较低的夜间静态血压时间范围 (TIR) 与原发性阿尔多斯顿症 (PA) 患者的心血管问题有关. 改善夜间血压控制可能会降低这一群体心血管事件的风险.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 高血压研究 高血压研究
背景情况:
- 原发性阿尔多斯特隆症 (PA) 是二次高血压的常见原因之一.
- 高血压与心血管风险增加有关,但血压控制指标的作用尚未完全理解.
研究的目的:
- 调查血压 (BP) 时间范围 (TIR) 与原发性阿尔多斯特主义 (PA) 患者的复合心血管结果之间的关联.
主要方法:
- 47名PA患者的队列接受了24小时的门诊血压监测 (ABPM) 和心血管结果评估.
- 收集的数据包括血压参数,药物使用和临床特征.
主要成果:
- 患有复合心血管结局的患者夜间缩血压BP TIR较低 (31.2%对11.5%,p=0.02),酒精摄入率更高.
- 调整后勤回归显示,夜间缩BP TIR与复合心血管结果有显著的关联 (OR=0.92 [0.86,0.99]).
结论:
- 夜间缩BP TIR是PA患者复合心血管结果的重要预测因素.
- 这一发现凸显了夜间血压监测和控制在控制PA心血管风险方面的重要性.
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