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Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue
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使用ex vivo桃体器官来研究记忆B细胞

Zachary W Wagoner1, Mahina Tabassum Mitul1, Lisa E Wagar2

  • 1Department of Physiology and Biophysics, Institute for Immunology, Center for Virus Research, and Vaccine R&D Center, University of California Irvine, Irvine, CA, USA.

Methods in molecular biology (Clifton, N.J.)
|July 17, 2024
PubMed
概括

需要新的工具来研究记忆B细胞 (MBCs) 和它们在抗击感染中的作用. 这项研究引入了一个人体淋巴细胞组织器官系统,用于在自然环境中分析MBC,并提供对免疫反应的见解.

关键词:
抗原特异性B细胞的抗原特异性B细胞人类免疫学 人类免疫学免疫性有机体 免疫性有机体淋巴状组织组织的淋巴状组织组织.接种疫苗后的反应

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Cells of the Adaptive Immune Response01:23

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The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
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