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人类B细胞受体谱的序列测序

Prasanti Kotagiri1, Rachael J M Bashford-Rogers2,3, Vanessa L Bryant4,5,6

  • 1Immunology Alfred Hospital, Central Clinical School, Monash University, Melbourne, VIC, Australia. prasanti.kotagiri@monash.edu.

Methods in molecular biology (Clifton, N.J.)
|July 17, 2024
PubMed
概括

高通量测序揭示了B细胞受体 (BCR) 的复杂性,但面临偏差. 这项研究优化了BCR图书馆的准备,以便在健康和疾病中准确,可重现的分析B细胞免疫力.

关键词:
在B细胞内存中,B细胞的记忆B细胞受体受体 B细胞受体受体在BCR的曲目中,BCR的曲目目目录.细胞分类 细胞分类人类B细胞是人类B细胞.下一代测序测序是什么

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Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
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