心脏病评分系统作为老年COVID-19患者死亡率的预测指标
Yudi Her Oktaviono1, Makhyan Jibril Al Farabi2, Aurelia Regina3
1Department of Nursing Management, Universitas Airlangga, Surabaya,.
JPMA. The Journal of the Pakistan Medical Association
|July 17, 2024
概括
一个新的心脏评分系统可以预测冠状病毒疾病-2019 (COVID-19) 的老年患者的死亡率. 该工具使用心电图的发现来识别住院期间高危人群.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 冠状病毒疾病-2019 (COVID-19) 构成显著的死亡风险,特别是在老年人群中.
- 在严重的COVID-19病例中经常观察到心脏并发症,影响预后.
- 需要有效的工具来识别高风险的老年COVID-19患者,以便及时干预.
研究的目的:
- 开发和验证心脏学评分系统,用于预测COVID-19诊断的老年患者的死亡率.
- 确定特定的心电图 (ECG) 发现,与此人口中死亡风险增加有关.
- 为临床医生提供一个实用的工具,以评估老年COVID-19患者的预后.
主要方法:
- 2020年3月至2021年4月期间入院的老年COVID-19患者的回顾性队列研究.
- 分析临床数据,并发症,心电图和胸部X射线发现.
- 基于通过统计分析确定的显著预测因素的评分系统的开发 (SPSS 26).
主要成果:
- 分析了322名老年COVID-19患者 (平均年龄66岁) 的数据;17.1%的人在住院期间死亡.
- 确定了五个重要的心脏变量:心脏壮大,鼻高心率,ST段异常,病态T波逆转和轴偏差.
- 开发的评分系统显示曲线下面的面积为0.86,切线≤4,为死亡率预测提供89%的灵敏度和69%的特异性.
结论:
- 一个新的心脏病评分系统有效预测老年COVID-19患者的死亡率.
- 该系统利用在住院期间随时可用的心脏病发现.
- 这种工具有可能改善老年COVID-19病例的风险分层和患者管理.
相关概念视频
01:20Blood Studies for Cardiovascular System I: Cardiac Biomarkers
133
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
133
01:29Electrocardiogram
2.3K
An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
2.3K
01:23Assessment of the Cardiovascular System I: Subjective Data
309
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
309
01:22Heart Failure Drugs: β-Blockers
336
β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and adrenaline (ADR). They have several beneficial effects in heart failure treatment. They reduce heart rate, the force of contraction, and cardiac muscle relaxation. They also slow the atrial-ventricular conduction rate and raise the threshold for arrhythmias. The concentration of β-blockers determines their effects on bronchodilation,...
336
01:19Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
73
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
73