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识别肺栓塞 - 膝关节全置换后高风险患者:系统性审查
Jannatin Nisa Arnindita1, Muhammad Hanun Mahyuddin2, Pandit Bagus Tri Saputra1
1Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Airlangga - Dr Soetomo General Academic Hospital, Surabaya, Indonesia.
JPMA. The Journal of the Pakistan Medical Association
|July 17, 2024
概括
肺栓塞 (PE) 是全膝关节置换 (TKR) 后的一种罕见但严重的并发症. 识别风险因素可以帮助预防这种疾病,死亡率很高.
科学领域:
- 整形外科手术 整形外科手术
- 心血管医学 心血管医学
- 医疗信息学 医疗信息学
背景情况:
- 肺栓塞 (PE) 是骨科手术后的一个重大问题.
- 全膝关节置换 (TKR) 手术存在发展PE的风险.
- 了解TKR患者的PE发生率和风险因素对于患者的治疗结果至关重要.
研究的目的:
- 为了确定发生率,发病,风险因素和与肺栓塞相关的死亡率,在接受全膝关节置换的患者中.
- 为了确定患者的关键特征和并发症,这些特征和并发症增加了TKR后PE的风险.
- 为预防策略提供信息,并优化化疗.
主要方法:
- 对1977年至2022年9月发表的研究进行了系统审查.
- 搜索的数据库包括PubMed,ScienceDirect,Scopus和Crossref. 这些数据库的搜索内容包括:
- 偏差风险和证据质量分别使用"柯克兰手册"和"纽卡斯尔-太华尺度"进行评估.
主要成果:
- 对66项涉及1300多万TKR患者的研究进行分析,发现PE发病率为0.58% (76515例).
- 勃起前列腺的发病时间在手术后2至150天之间.
- 风险因素包括年龄较大,糖尿病,BMI较高,心房动,以前的静脉血栓栓塞,高血压和心力衰竭. 死亡率从10.53%到100%不等.
结论:
- 肺栓塞是全膝关节置换术的罕见但极具致命性的并发症.
- 早期识别已识别的风险因素对于临床管理至关重要.
- 根据风险评估优化化疗法可帮助预防TKR后的PE.
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