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实证模型可变性:开发一种新的全球优化方法来填充压缩和压缩混合规则

Theo Tait1, Mohammad Salehian1, Magdalini Aroniada2

  • 1Centre for Continuous Manufacturing and Advanced Crystallization (CMAC), University of Strathclyde, Glasgow G1 1RD, UK; Strathclyde Institute of Pharmacy & Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UK.

International journal of pharmaceutics
|July 17, 2024
PubMed
概括

这项研究评估了制药粉末紧缩模型,发现性能随着更高的活性药物成分 (API) 负载而下降. 一种新的全球优化方法提高了预测准确性,并减少了对新混合物的实验需求.

关键词:
经验模型是经验模型.全球优化全球优化混合规则 混合规则一个平板电脑压缩片.一个平板电脑压缩平板电脑.

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