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Updated: Jun 20, 2025

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Mettl3-m6A-YTHDF1轴促进了代谢功能障碍相关的脂肪性肝病中的线粒体功能障碍

Shuowen Wang1, Wanyu Zhang2, Zijun Wang3

  • 1Beijing Tongren Hospital, Capital Medical University, Beijing 100176, China; Capital Institute of Pediatrics, Beijing 100020, China.

Cellular signalling
|July 17, 2024
PubMed
概括

N6-甲基氨酸 (m6A) 修改影响了代谢功能障碍相关的脂肪性肝病 (MASLD) 的肝脏健康. 针对Mettl3-m6A-YTHDF1通路可以改善线粒体功能并缓解MASLD.

关键词:
与代谢功能障碍相关的脂肪性肝病.甲基转移酶类似于3甲基转移酶线粒体呼吸链中的线粒体呼吸链.这是一种N6-甲基氨酸.非酒精性脂肪性肝病是什么?YTH N6-甲基氨酸RNA结合蛋白 1 1

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