慢性肺炎与独立于表型的心血管疾病风险增加有关
Kolton Cobb1, Jonathan Kenyon1, Juan Lu2
1Department of Kinesiology and Health Sciences, Virginia Commonwealth University, Richmond, Virginia, USA.
Respirology (Carlton, Vic.)
|July 17, 2024
概括
患有慢性阻塞性肺病 (COPD) 的患者在所有表型中都有更高的心血管疾病风险. 结合慢性支气管炎和肺气表型显示,心血管疾病风险增加最为显著.
科学领域:
- 肺部医学 肺部医学
- 心脏病学 心脏病学
- 流行病学 流行病学
背景情况:
- 慢性阻塞性肺病 (COPD) 是一个主要的全球健康问题,经常与心血管疾病同时发生.
- 了解COPD特定表型对心血管疾病 (CVD) 风险的影响对于有针对性的干预至关重要.
研究的目的:
- 调查COPD患者心血管疾病的患病率,根据肺气和慢性支气管炎的表型进行区分.
- 通过使用大型,具有全国代表性的数据集,分析与不同COPD表型相关的CVD风险.
主要方法:
- 利用了来自国家健康和营养检查调查 (1999-2018) 的31560名成年人 (2504名COPD患者) 的数据.
- 使用统计分析来比较COPD表型和健康对照中的心血管疾病患病率.
主要成果:
- 慢性肺炎患者显著增加心血管疾病的风险,包括冠心病,心力衰竭,心肌梗塞和中风.
- 与非COPD患者相比,患有慢性支气管炎的个体患病几率是1.76倍,肺气患病几率是2.31倍,综合表型患心血管疾病的几率是2.98倍.
- 同时的慢性支气管炎和肺气表型显示出最高的心血管疾病风险.
结论:
- 无论表型如何,COPD患者始终表现出患心血管疾病的风险较高.
- 同时出现肺气和慢性支气管炎的表型与心血管疾病风险的最大增加有关.
- 强调需要提高COPD诊断患者的意识和系统的心血管查.
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