在无透镜超薄纤维束尖端的ptycho-endoscopy上使用无透镜的超薄纤维束
Pengming Song1, Ruihai Wang2, Lars Loetgering3
1Department of Biomedical Engineering, University of Connecticut, Storrs, CT, 06269, USA. pengming.song@uconn.edu.
Light, science & applications
|July 17, 2024
概括
合成孔径透视内镜 (SAPE) 使用手持式纤维捆绑来捕捉衍射模式,为超高分辨率的超光学极限超越的微内镜成像创建一个大型虚拟孔径.
科学领域:
- 光学和光子学 在光学和光子学.
- 生物医学成像技术 生物医学成像技术
- 显微镜的使用方法
背景情况:
- 合成光圈雷达 (SAR) 通过合成大光圈来实现高分辨率.
- 微内镜成像受限于光的衍射和探针的物理尺寸.
- 现有的内镜技术难以实现高分辨率和扩展的视野深度.
研究的目的:
- 为了引入微内镜成像的合成孔径ptycho-endoscopy (SAPE).
- 为了克服内镜成像中的衍射极限.
- 增强内镜应用的空间带宽产品和视野深度.
主要方法:
- SAPE采用无镜头纤维束端来记录连贯的衍射模式.
- 手持操作诱导位置变化,类似于SAR的运动,以获得图形图.
- 低级空间时空分解纠正手动和纤维曲器件.
主要成果:
- SAPE可以解决548nm的线宽,超过了衍射极限.
- 实现了空间带宽乘积的~110万有效像素,增加了36倍.
- 演示了超过2厘米的扩展视野深度,并具有重新聚焦能力.
结论:
- SAPE 能够实现超高分辨率的微内镜成像,超出衍射极限.
- 该技术显著提高了成像分辨率和视野深度.
- 在医疗诊断和工业检查中为基于纤维和远端芯片内镜开辟了新的途径.
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