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Updated: Jun 20, 2025

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
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Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events

Published on: May 13, 2019

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柯凯恩综合征与转录延长过程中停滞的RNA聚合酶II诱导的R-循环升高有关

Xuan Zhang1,2, Jun Xu3,4,5, Jing Hu6

  • 1Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.

Nature communications
|July 17, 2024
PubMed
概括

考凯恩综合征B组 (CSB) 蛋白质对于推动RNA聚合酶II (RNAPII) 延长至关重要. 通过促进R循环的形成,特别是在人类神经元基因中,CSB缺乏导致基因组不稳定.

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