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Updated: Jun 20, 2025

Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations
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一种合成抗生素类别,具有深度优化的设计,用于克服细菌耐药性

Jin Feng1, Youle Zheng2, Wanqing Ma2

  • 1National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues, Huazhong Agricultural University, Wuhan, Hubei, China.

Nature communications
|July 17, 2024
PubMed
概括

一种新型抗微生物药物F8对抗生素耐药细菌表现出广泛的活性. 这种候选药物有效地对抗感染,并通过向甲甲基转移酶 (arcB) 来缓解耐药性发展.

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