口腔内镜肌肉切除术对内镜压力研究综合系统的影响
Yohei Nishikawa1, Haruhiro Inoue1, Ippei Tanaka1
1Digestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, Japan.
概括
内镜压力研究综合系统 (EPSIS) 有效地测量了在口腔内镜肌切除术 (POEM) 之后,食道下功能发生的变化. 这种诊断工具客观地评估了POEM.
科学领域:
- 胃肠病学 胃肠病学
- 内镜诊断的诊断方法
- 评估手术结果的评估.
背景情况:
- 阿哈拉西亚是口腔内镜肌切除术 (POEM) 的首要症状.
- 内镜压力研究综合系统 (EPSIS) 评估了下消化道 (LES) 功能.
- 虽然EPSIS已在诊断阿喀拉西亚方面表现出有效性,但其在评估POEM结果方面的实用性较不确立.
研究的目的:
- 评估EPSIS在检测LES功能在POEM前后变化的有效性.
- 确定EPSIS是否可以作为评估POEM临床影响的客观工具.
主要方法:
- 对50名接受POEM治疗的患者 (2022年1月 - 2023年12月) 的回顾性分析.
- 术前和术后2个月进行的EPSIS.
- 胃内压力 (IGP) 参数的比较 (最大IGP,IGP差异,波形梯度) 在POEM前和后的状态之间以及在手术后的GERD和非GERD组之间.
主要成果:
- 与POEM前相比,POEM后观察到最大IGP,IGP差异和波形梯度的显著减少.
- 术后波形梯度在患有GERD的患者中明显较低,与没有患有GERD的患者相比.
- EPSIS参数显示了显著的变化,表明POEM后 LES功能有所改善.
结论:
- EPSIS是一个有效的客观诊断工具,用于评估POEM的功能结果.
- 通过EPSIS,可以量化POEM治疗achalasia后的生理变化.
- 该研究支持将EPSIS整合到POEM的例行评估中.
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