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Updated: Jun 20, 2025

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
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Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events

Published on: May 13, 2019

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在DNA损伤时RNA聚合酶II的差异处理与转录合修复综合征的严重程度相关

Camila Gonzalo-Hansen1, Barbara Steurer1, Roel C Janssens1

  • 1Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.

Nucleic acids research
|July 18, 2024
PubMed
概括

无法从DNA损伤中清除停滞的RNA聚合酶II (Pol II),而不仅仅是缺陷的转录合核酸切除修复 (TC-NER),导致严重的柯凯恩综合征. 紫外线敏感综合征和柯凯恩综合征之间的Pol II清除机制不同.

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