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对与人类扩展光谱β-lactamase产生的Enterobacteriaceae相关的因素的专题描述

Jamie Goltz^1,2, Carl Uhland², Sydney Pearce¹

¹Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, ON.

Canada communicable disease report = Releve des maladies transmissibles au Canada

|July 18, 2024

概括

加拿大人的扩展谱β-乳糖酶 (ESBL) 感染与各种暴露途径有关. 本次审查确定了医疗保健和抗生素使用等关键因素,强调了需要采用多部门方法来打击抗菌素耐药性.

科学领域:

公共卫生公共卫生
传染性疾病传染性疾病
抗微生物耐药性抗微生物耐药性

背景情况:

产生扩展光谱β-乳糖酶 (ESBL) 的肠道细菌在加拿大引起严重感染.
人类暴露于产生ESBL的 Enterobacteriaceae 通过相互连接的途径发生.
了解这些途径对于保护加拿大人免受抗菌素耐药性感染至关重要.

研究的目的:

专题描述与ESBL产生的Enterobacteriaceae殖民,携带和/或人类感染相关的因素.
分析相关研究的研究特征.
在高人类发展指数的国家制定减轻ESBL暴露的策略.

主要方法:

进行了全面的范围审查.
搜索了四个主要的数据库 (PubMed,CAB Direct,科学网络,EBSCOhost).
选了相关的文章,并根据主题分组并描述了所识别的因素.

主要成果:

审查了381篇文章,确定了13个因素主题,包括抗菌药物的使用,动物,医疗保健和人口统计.
人口统计,医疗保健,抗生素使用和并发症是最常见的主题.
大多数研究集中在医院环境 (86%) 和ESBL感染 (52%).

结论:

本次综述强调了已知因素 (如医疗保健) 和未经探索的领域 (如饮食,与动物接触).
确定的主题跨越人类,动物和环境的背景.
为了减轻抗菌素耐药性暴露,必须采取多部门的方法.

关键词:

这就是ESBL.它们是Enterobacteriaceae的细菌.人类人类人类人类人类人类.知识综合知识综合有关风险因素的风险因素.

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